Sulfanyl substituted phenyl methanones as glycine transporter 1 (GlyT-1) inhibitors for the treatment of neurological and neuropsychiatric disorders

Details for Australian Patent Application No. 2005324023 (hide)

Owner F.Hoffmann-La Roche AG

Inventors Pinard, Emmanuel; Jolidon, Synese; Narquizian, Robert; Norcross, Roger David

Agent Spruson & Ferguson

Pub. Number AU-A-2005324023

PCT Pub. Number WO2006/072435

Priority 05100066.9 06.01.05 EP

Filing date 28 December 2005

Wipo publication date 13 July 2006

International Classifications

C07D 295/18 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C07D 213/74 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

Event Publications

9 August 2007 PCT application entered the National Phase

  PCT publication WO2006/072435 Priority application(s): WO2006/072435

30 August 2007 Change of Name(s) of Applicant(s), Section 104

  F.Hofmann-La Roche AG The name of the applicant has been changed to F. Hoffmann-La Roche AG

14 January 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(a). A direction to request examination has been given for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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