Antibodies against clostridium difficile toxins and uses thereof

Details for Australian Patent Application No. 2005320349 (hide)

Owner University of Massachusetts Medarex, Inc.

Inventors Hernandez, Hector Javier; Ambrosino, Donna; Broering, Theresa; Thomas, William D., Jr; Lowy, Israel; Babcock, Gregory J.; Molrine, Deborah; Mandell, Robert; Zhang, Hui-Fen

Agent Shelston IP

Pub. Number AU-B-2005320349

PCT Pub. Number WO2006/121422

Priority 60/613,854 28.09.04 US; 60/542,357 06.02.04 US

Filing date 4 February 2005

Wipo publication date 24 August 2006

Acceptance publication date 8 April 2010

International Classifications

A61K 39/08 (2006.01) Medicinal preparations containing antigens or antibodies - Clostridium, e.g. Clostridium tetani

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 1/00 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/12 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

C07K 16/12 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from bacteria

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/13 (2006.01) Mutation or genetic engineering - Immunoglobulins

A61P 31/04 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Event Publications

24 August 2006 Application Open to Public Inspection

  Published as AU-B-2005320349

24 August 2006 PCT application entered the National Phase

  PCT publication WO2006/121422 Priority application(s): WO2006/121422

7 August 2008 Corrigenda

  PCT applications that have entered the National Phase - Name Index Under the name University of Massachusetts and Medarex, Inc., Application No. 2005320349, under INID(43), correct the date to read 16.11.06

23 April 2009 Corrigenda

  PCT applications that have entered the National Phase - Name Index Under the name University of Massachusetts and Medarex, Inc., Application No. 2005320349, under INID(43), correct the date to read 16.11.06

8 April 2010 Application Accepted

  Published as AU-B-2005320349

22 April 2010 Corrigenda

  Applications Accepted - Name Index Under the names University of Massachusetts and Medarex, Inc., Application No. 2005320349, under INID (72) add the co-inventor Graziano, Robert

12 August 2010 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 28 May 2010. Address for service in Australia - Shelston IP Level 21 60 Margaret Street Sydney NSW 2000

18 November 2010 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 18 Oct 2010. Address for service in Australia - Shelston IP Level 21 60 Margaret Street Sydney NSW 2000 2006

2 December 2010 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 28 May and 16 Jul 2010

10 March 2011 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 18 Oct 2010 2006

17 March 2011 Standard Patent Sealed

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