Owner Alnylam Pharmaceuticals, Inc.

Inventors Hadwiger, Philipp; Heidenreich, Olaf; Vornlocher, Hans-Peter

Agent Griffith Hack

Pub. Number AU-B-2005316384

PCT Pub. Number WO2006/066158

Priority 60/698,414 12.07.05 US; 60/635,936 14.12.04 US; 60/668,392 05.04.05 US

Filing date 14 December 2005

Wipo publication date 22 June 2006

Acceptance publication date 9 February 2012

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/04 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 15/113 (2010.01) Mutation or genetic engineering - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids