Owner Janssen Pharmaceutica N.V.

Inventors Embrechts, Werner Constant Johan; Van Brandt, Sven Franciscus Anna; Freyne, Eddy Jean Edgard; Rombouts, Frederik Jan Rita; Van Emelen, Kristof; Willems, Marc

Agent Shelston IP

Pub. Number AU-B-2005313348

PCT Pub. Number WO2006/061415

Priority 04106384.3 08.12.04 EP; 60/634,291 08.12.04 US

Filing date 8 December 2005

Wipo publication date 15 June 2006

Acceptance publication date 6 October 2011

C07D 487/08 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

A61K 31/505 (2006.01) - Pyrimidines

A61P 35/00 (2006.01) Antineoplastic agents

C07D 209/00 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 221/00 (2006.01) Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

C07D 239/00 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 241/00 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 259/00 (2006.01) Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms

C07D 273/00 (2006.01) Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups

C07D 487/22 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 498/18 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms