Owner Ligand Pharmaceuticals Incorporated

Inventors Chen, Jyun-Hung; Phillips, Dean P.; Nguyen, Bao N.; McNeill, Matthew H.; Kallel, Adam E.; Dalgard, Jackline E.; Miller, Todd A.; Zhi, Lin; Penulair, Richard J.; Ruppar, Daniel A.; Lau, Thomas

Agent Griffith Hack

Pub. Number AU-B-2005299720

PCT Pub. Number WO2006/047344

Priority 60/675,001 25.04.05 US; 60/621,879 25.10.04 US

Filing date 21 October 2005

Wipo publication date 4 May 2006

Acceptance publication date 4 February 2010

C07D 277/54 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

A61K 31/404 (2006.01)

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/472 (2006.01) - Non-condensed isoquinolines, e.g. papaverine

A61P 7/00 (2006.01) Drugs for disorders of the blood or the extracellular fluid

C07D 209/40 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 217/24 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 239/60 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 405/04 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group