Owner Amgen Inc.

Inventors Sitney, Karen C.; Xiong, Fei; Gegg, Colin

Agent Shelston IP

Pub. Number AU-B-2005289685

PCT Pub. Number WO2006/036834

Priority 60/612,680 24.09.04 US

Filing date 23 September 2005

Wipo publication date 6 April 2006

Acceptance publication date 16 July 2009

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

C07K 16/00 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 19/00 (2006.01) Hybrid peptides

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 15/62 (2006.01) Mutation or genetic engineering - DNA sequences coding for fusion proteins

C12N 15/70 (2006.01) Mutation or genetic engineering - Vectors or expression systems specially adapted for E. coli

C07K 14/475 (2006.01) Peptides having more than 20 amino acids

C07K 14/505 (2006.01) Peptides having more than 20 amino acids

C07K 14/515 (2006.01) Peptides having more than 20 amino acids

C07K 14/52 (2006.01) Peptides having more than 20 amino acids