Beta-gluguronidase cleavable prodrugs of O6-alkylguanine-DNA alkyltransferase inactivators

Details for Australian Patent Application No. 2005282562 (hide)

Owner The Pen State Research Foundation Goverment of the United States of America Represented by The Secretary, Department of Health and Human Services

Inventors Loktionova, Natalia A.; Moschel, Robert C.; Wei, Guangping; Pegg, Anthony E.

Agent Fisher Adams Kelly

Pub. Number AU-A-2005282562

PCT Pub. Number WO2006/029065

Priority 60/608,045 08.09.04 US

Filing date 6 September 2005

Wipo publication date 16 March 2006

International Classifications

C07H 15/26 (2006.01) Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals

A61K 31/7076 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

C07H 19/16 (2006.01) Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical

Event Publications

29 March 2007 PCT application entered the National Phase

  PCT publication WO2006/029065 Priority application(s): WO2006/029065

19 April 2007 Amendment Made

  The nature of the amendment is: Amend the invention title to read Beta-glucuronidase cleavable prodrugs of O6-alkylguanine-DNA alkyltransferase inactivators

19 April 2007 Change of Name(s) of Applicant(s), Section 104

  The Pen State Research Foundation; Goverment of the United States of America Represented by The Secretary, Department of Health and Human Services The name of the applicant has been changed to The Penn State Research Foundation; Government of the United States of America Represented by The Secretary, Department of Health and Human Services

24 September 2009 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(a). A direction to request examination has been given for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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