Method for preparing 5-`4-(2-hydroxy-ethyl)-3,5-dioxo-4,5-dih ydro-3H-`1,2,4!-triazin-2-YK!benzamide derivatives with P2x7 inhibiting activity by reaction of the derivative unsubstituted in 4-position of the triazine with an oxiran in the presence of a lewis acid

Details for Australian Patent Application No. 2005258924 (hide)

Owner Pfizer Products Inc.

Inventors Leonard, Jason Albert; Li, Zhengong Bryan; Urban, Frank John; Li, Zheng Jane

Agent Allens Arthur Robinson

Pub. Number AU-A-2005258924

PCT Pub. Number WO2006/003513

Priority 60/669,756 08.04.05 US; 60/583,813 29.06.04 US

Filing date 17 June 2005

Wipo publication date 12 January 2006

International Classifications

C07D 253/06 (2006.01) Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group

A61K 31/53 (2006.01) - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

Event Publications

4 January 2007 PCT application entered the National Phase

  PCT publication WO2006/003513 Priority application(s): WO2006/003513

2 July 2009 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(a). A direction to request examination has been given for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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