Owner Isis Pharmaceuticals, Inc.

Inventors Dande, Prasad; Bhat, Balkrishen; Prakash, Thazha P.; Griffey, Richard H.; Allerson, Charles; Swayze, Eric E.

Agent Pizzeys

Pub. Number AU-B-2005252663

PCT Pub. Number WO2005/121372

Priority 60/584,045 29.06.04 US; 10/946,147 20.09.04 US; PCT/ US2004/017522 03.06.04 US; PCT/ US2004/017485 03.06.04 US; 10/859,825 03.06.04 US; 60/607,927 07.09.04 US

Filing date 2 June 2005

Wipo publication date 22 December 2005

Acceptance publication date 7 July 2011

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/04 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids