Owner Amgen Inc.

Inventors Tempest, Paul A.; Kim, Joseph L.; Patel, Vinod F.; Zhu, Xiaotian; Chaffee, Stuart C.; Bellon, Steven; Johnson, Rebecca E.; Albrecht, Brian K.; Romero, Karina; Cee, Victor J.; Deak, Holly L.; Olivieri, Philip R.; Nguyen, Hanh Nho; Cheng, Yuan; Hodous, Brian L.; Xi, Ning; Geuns-Meyer, Stephanie D.

Agent Shelston IP

Pub. Number AU-B-2005245386

PCT Pub. Number WO2005/113494

Priority 60/569,193 07.05.04 US

Filing date 9 May 2005

Wipo publication date 1 December 2005

Acceptance publication date 27 November 2008

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61K 31/4439 (2006.01)

A61K 31/497 (2006.01)

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/53 (2006.01) - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

C07D 213/73 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 407/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups