Proline CCI-779 (proline-rapamycin 42-ester with 2,2-bis (hydroxymethyl) propionic acid) and two-step enzymatic synthesis of proline CCI-779 and CCI779 using microbial lipase

Details for Australian Patent Application No. 2005233612 (hide)

Owner Wyeth

Inventors Chew, Warren; Ruppen, Mark E.; Gu, Jianxin; Raveendranath, Panolil; Shaw, Chia-Cheng

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-A-2005233612

PCT Pub. Number WO2005/100366

Priority 60/562,069 14.04.04 US; 60/623,594 29.10.04 US

Filing date 12 April 2005

Wipo publication date 27 October 2005

International Classifications

C07D 498/18 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07F 7/18 (2006.01) Compounds containing elements of the 4th Group of the Periodic System

Event Publications

2 November 2006 PCT application entered the National Phase

  PCT publication WO2005/100366 Priority application(s): WO2005/100366

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