Modified polynucleotides for reducing off-target effects in RNA interference

Details for Australian Patent Application No. 2005230850 (hide)

Owner Merck & Co., Inc. Dharmacon, Inc.

Inventors Leake, Devin; Fedorov, Yuriy; Marshall, William; Reynolds, Angela; Khvorova, Anastasia

Agent Griffith Hack

Pub. Number AU-B-2005230850

PCT Pub. Number WO2005/097992

Priority 60/630,228 22.11.04 US; 11/019,831 22.12.04 US; PCT/US04/10343 01.04.04 US

Filing date 31 March 2005

Wipo publication date 20 October 2005

Acceptance publication date 17 September 2009

International Classifications

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

A01H 1/00 (2006.01) Processes

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 15/82 (2006.01) Mutation or genetic engineering - for plant cells

Event Publications

23 November 2006 PCT application entered the National Phase

  PCT publication WO2005/097992 Priority application(s): WO2005/097992

6 August 2009 Assignment before Grant

  Dharmacon, Inc. The application has been assigned to Merck & Co., Inc.; Dharmacon, Inc.

17 September 2009 Application Accepted

  Published as AU-B-2005230850

8 October 2009 Application for Amendment

  The nature of the amendment is: Add co-inventor Linsley, Peter S. and delete co-inventor Fedorov, Yuriy. Address for service in Australia - Griffith Hack Level 3 509 St Kilda Road Melbourne VIC 3004

21 January 2010 Amendment Made

  The nature of the amendment is: Add co-inventor Linsley, Peter S. and delete co-inventor Fedorov, Yuriy

28 January 2010 Standard Patent Sealed

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