Histone deacetylase inhibitor prodrugs

Details for Australian Patent Application No. 2005230682 (hide)

Owner Merck HDAC Research, LLC

Inventors Witter, David J.; Miller, Thomas A.; Belvedere, Sandro

Agent Cullens

Pub. Number AU-B-2005230682

PCT Pub. Number WO2005/097747

Priority 60/559,715 05.04.04 US

Filing date 5 April 2005

Wipo publication date 20 October 2005

Acceptance publication date 21 October 2010

International Classifications

C07C 259/06 (2006.01) Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups

A61K 31/16 (2006.01) - Amides, e.g. hydroxamic acids

A61K 31/165 (2006.01) - having aromatic rings, e.g. colchicine, atenolol, progabide

A61K 31/44 (2006.01) - Non-condensed pyridines

C07C 271/22 (2006.01) Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07D 213/00 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/80 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/82 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 215/38 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 215/40 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 215/42 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

Event Publications

16 November 2006 PCT application entered the National Phase

  PCT publication WO2005/097747 Priority application(s): WO2005/097747

11 December 2008 Assignment before Grant

  Aton Pharma, Inc. The application has been assigned to Merck HDAC Research, LLC

21 October 2010 Application Accepted

  Published as AU-B-2005230682

17 February 2011 Standard Patent Sealed

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