Owner Methylgene Inc.

Inventors Moradei, Oscar; Frechette, Sylvie; Raeppel, Stephane; Isakovic, Ljubomir; Gaudette, Frederic; Delorme, Daniel; Leit, Silvana; Paquin, Isabelle; Vaisburg, Arkadii; Bouchain, Giliane; Zhou, Zhihong

Agent Spruson & Ferguson

Pub. Number AU-B-2005225471

PCT Pub. Number WO2005/092899

Priority 60/556,828 26.03.04 US; 11/090,713 25.03.05 US; PCT/IB05/00802 25.03.05 IB

Filing date 29 March 2005

Wipo publication date 6 October 2005

Acceptance publication date 12 May 2011

C07D 495/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/36 (2006.01)

A61K 31/40 (2006.01) - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 31/428 (2006.01) - condensed with carbocyclic rings

A61K 31/4439 (2006.01)

A61K 31/455 (2006.01) - Nicotinic acid, i.e. niacin

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/505 (2006.01) - Pyrimidines

A61K 31/5377 (2006.01)

C07C 237/40 (2006.01) Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

C07D 209/08 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/14 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/16 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/22 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/38 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/74 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 231/38 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 235/16 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings

C07D 237/20 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 239/26 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/48 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings