Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same

Details for Australian Patent Application No. 2005225039 (hide)

Owner Gilead Sciences, Inc.

Inventors Kernan, Michael R; Rohloff, John C; Chapman, Harlan H; Lee, William A; Sparacino, Mark L; He, Gong-Xin; Becker, Mark W; Prisbe, Ernest J; Eisenberg, Eugene J; Cihlar, Tomas

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2005225039

Parent 2001282941

Filing date 18 October 2005

Wipo publication date 10 November 2005

Acceptance publication date 25 September 2008

International Classifications

C07H 21/00 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

A61K 31/664 (2006.01) - Amides of phosphorus acids

A61K 31/675 (2006.01) - having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

A61P 31/12 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 31/18 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 (2006.01) Antineoplastic agents

C07F 9/6561 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

C07H 19/10 (2006.01) Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical

C07H 19/20 (2006.01) Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical

C12Q 1/18 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - Testing for antimicrobial activity of a material

G01N 33/15 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

G01N 33/50 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay

Event Publications

3 November 2005 Complete Application Filed

10 November 2005 Application Open to Public Inspection

  Published as AU-B-2005225039

25 September 2008 Application Accepted

  Published as AU-B-2005225039

22 January 2009 Standard Patent Sealed

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