Owner Alnylam Pharmaceuticals, Inc.

Inventors De Fougerolles, Antonin; Rajeev, Kallanthottahil G.; Hadwiger, Phillipp; Manoharan, Muthiah; Frank-Kamenetsky, Maria

Agent FB Rice

Pub. Number AU-B-2005222902

PCT Pub. Number WO2005/089224

Priority 60/647,191 25.01.05 US; 60/552,620 12.03.04 US; 60/559,824 05.04.04 US

Filing date 11 March 2005

Wipo publication date 29 September 2005

Acceptance publication date 10 June 2010

C07H 21/04 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61K 9/00 (2006.01) Medicinal preparations characterised by special physical form

A61K 47/02 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Inorganic compounds

A61K 47/10 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Alcohols

A61K 47/12 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Carboxylic acids