Owner Astellas Pharma Inc.

Inventors Moritomo, Ayako; Itahana, Hirotsune; Matsuzawa, Takaho; Akuzawa, Shinobu; Fujiyasu, Jiro; Koga, Yuji; Okazaki, Toshio; Harada, Koichiro; Watanabe, Toshihiro; Oku, Makoto; Yamada, Hiroyoshi

Agent Davies Collison Cave

Pub. Number AU-A-2005214249

PCT Pub. Number WO2005/080322

Priority 2004-044122 20.02.04 JP

Filing date 17 February 2005

Wipo publication date 1 September 2005

C07C 279/22 (2006.01) Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups

A61K 31/166 (2006.01) - having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/351 (2006.01) - not condensed with another ring

A61K 31/352 (2006.01) - condensed with carbocyclic rings, e.g. cannabinols, methantheline

A61K 31/357 (2006.01) - having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel

A61K 31/385 (2006.01) - having two or more sulfur atoms in the same ring

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/4168 (2006.01)

A61K 31/4196 (2006.01) - 1,2,4-Triazoles

A61K 31/421 (2006.01) - 1,3-Oxazoles, e.g. pemoline, trimethadione

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/438 (2006.01) - the ring being spiro-condensed with carbocyclic or heterocyclic ring systems

A61P 25/06 (2006.01) Drugs for disorders of the nervous system

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 221/20 (2006.01) Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

C07D 233/88 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 249/08 (2006.01) Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 257/04 (2006.01) Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

C07D 263/28 (2006.01) Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D 277/18 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 277/28 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 307/94 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom