Owner Amgen Inc.

Inventors Borg, George; Buchanan, John L.; Dipietro, Lucian V.; Kim, Joseph L.; Weiss, Matthew; Xu, Shimin; McGowan, David C.; La, Daniel; Whittington, Douglas A.; Potashman, Michele; Booker, Shon; Tasker, Andrew; Graceffa, Russell; Choquette, Deborah; Germain, Julie; Bellon, Steven; Martin, Matthew W.; Masse, Craig E.; Xi, Ning; Kim, TaeSeong; Buckner, Willian H.; Habgood, Gregory J.; Cheng, Yuan; Chaffee, Stuart C.; Hodous, Brian L.; Patel, Vinod F.; Harmange, Jean-Christophe; Nunes, Joseph J.

Agent Shelston IP

Pub. Number AU-B-2005206571

PCT Pub. Number WO2005/070891

Priority 60/538,691 23.01.04 US

Filing date 24 January 2005

Wipo publication date 4 August 2005

Acceptance publication date 12 August 2010

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 215/233 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 215/38 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 215/48 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 215/54 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 217/24 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 237/34 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 239/30 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/34 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/46 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/84 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/94 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 407/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 215/22 Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems