New process for the synthesis of (1S)-4,5-dimethoxy-1-(methylaminomet hyl)-benzocyclobutane and addition salts thereof, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

Details for Australian Patent Application No. 2005200883 (hide)

Owner Les Laboratoires Servier

Inventors Lerestif, Jean-Michel; Brigot, Daniel; Lecouve, Jean-Pierre; Blanco, Isaac Gonzalez

Agent Allens Arthur Robinson

Pub. Number AU-B-2005200883

Priority 04.05453 19.05.04 FR

Filing date 18 February 2005

Wipo publication date 8 December 2005

Acceptance publication date 15 July 2010

International Classifications

C07D 223/16 (2006.01) Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom

A61K 31/55 (2006.01) - having seven-membered rings, e.g. azelastine, pentylenetetrazole

A61P 9/06 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

C07B 57/00 (2006.01) Separation of optically-active compounds

C07B 61/00 (2006.01) Other general methods

C07C 213/02 (2006.01) Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton

C07C 213/08 (2006.01) Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton

C07C 213/10 (2006.01) Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton

C07C 217/56 (2006.01) Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

C07C 217/58 (2006.01) Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

Event Publications

17 March 2005 Complete Application Filed

  Priority application(s): 04.05453 19.05.04 FR

8 December 2005 Application Open to Public Inspection

  Published as AU-B-2005200883

15 July 2010 Application Accepted

  Published as AU-B-2005200883

11 November 2010 Standard Patent Sealed

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