Zn2+ -chelating motif-tethered short - chain fatty acids as a novel class of histone deacetylase inhibitors

Details for Australian Patent Application No. 2004296764 (hide)

Owner The Ohio State University Research Foundation

Inventors Chen, Ching-Shih; Qiang, Lu

Agent Spruson & Ferguson

Pub. Number AU-B-2004296764

PCT Pub. Number WO2005/055928

Priority 60/526,348 02.12.03 US

Filing date 1 December 2004

Wipo publication date 23 June 2005

Acceptance publication date 28 April 2011

International Classifications

C07C 237/22 (2006.01) Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

A61K 31/167 (2006.01) - having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol

A61K 31/19 (2006.01)

A61K 31/4402 (2006.01) - only substituted in position 2, e.g. pheniramine, bisacodyl

C07C 237/42 (2006.01) Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

C07C 259/06 (2006.01) Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups

C07C 259/10 (2006.01) Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

Event Publications

27 July 2006 PCT application entered the National Phase

  PCT publication WO2005/055928 Priority application(s): WO2005/055928

28 April 2011 Application Accepted

  Published as AU-B-2004296764

25 August 2011 Standard Patent Sealed

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