Benzylether and benzylamino betasecretase inhibitors for the treatment of Alzheimer's disease

Details for Australian Patent Application No. 2004293416 (hide)

Owner Merck & Co., Inc.

Inventors Stauffer, Shaun R.; Rajapakse, Hemaka A.; Nantermet, Philippe G.; Young, Mary Beth; Selnick, Harold G.

Agent Spruson & Ferguson

Pub. Number AU-B-2004293416

PCT Pub. Number WO2005/051914

Priority 60/570,239 12.05.04 US; 60/602,434 18.08.04 US; 60/524,454 24.11.03 US

Filing date 19 November 2004

Wipo publication date 9 June 2005

Acceptance publication date 24 September 2009

International Classifications

A61K 31/44 (2006.01) - Non-condensed pyridines

C07C 255/46 (2006.01) Carboxylic acid nitriles

C07C 311/08 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07D 207/06 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/02 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/76 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 295/192 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

Event Publications

27 April 2006 PCT application entered the National Phase

  PCT publication WO2005/051914 Priority application(s): WO2005/051914

24 September 2009 Application Accepted

  Published as AU-B-2004293416

28 January 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under reg. 22.2I(2). This application has been accepted or advertised accepted. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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