Process for the manufacture of the calcium salt of rosuvatatin (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[ methyl(methylsulfonyl) amino]pyrimidin-5-yl](3R, 5S)-3,5-dihydroxyhept-6-enoic acid and crystalline intermediates thereof

Details for Australian Patent Application No. 2004285750 (hide)

Owner AstraZeneca UK Limited Shionogi & Company Limited

Inventors Laffan, David Dermot Patrick; Okada, Tetsuo; Horbury, John

Agent Davies Collison Cave

Pub. Number AU-B-2004285750

PCT Pub. Number WO2005/042522

Priority 0324791.3 24.10.03 GB

Filing date 22 October 2004

Wipo publication date 12 May 2005

Acceptance publication date 13 March 2008

International Classifications

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 405/06 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

Event Publications

11 May 2006 PCT application entered the National Phase

  PCT publication WO2005/042522 Priority application(s): WO2005/042522

13 March 2008 Application Accepted

  Published as AU-B-2004285750

10 July 2008 Standard Patent Sealed

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