Benzylether and benzylamino betasecretase inhibitors for the treatment of Alzheimer's disease

Details for Australian Patent Application No. 2004277981 (hide)

Owner Merck & Co., Inc.

Inventors Rajapakse, Hemaka Anthony; Nantermet, Philippe G.; Selnick, Harold G.

Agent Spruson & Ferguson

Pub. Number AU-B-2004277981

PCT Pub. Number WO2005/032471

Priority 60/508,369 03.10.03 US

Filing date 29 September 2004

Wipo publication date 14 April 2005

Acceptance publication date 1 October 2009

International Classifications

A61K 31/195 (2006.01)

C07C 255/57 (2006.01) Carboxylic acid nitriles

C07C 311/08 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07D 207/06 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 207/08 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/76 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 295/192 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 333/20 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 405/04 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

Event Publications

13 April 2006 PCT application entered the National Phase

  PCT publication WO2005/032471 Priority application(s): WO2005/032471

1 October 2009 Application Accepted

  Published as AU-B-2004277981

4 February 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under reg. 22.2I(2). This application has been accepted or advertised accepted. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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