Owner Kyowa Hakko Kirin Co., Ltd.

Inventors Soga, Shiro; Saito, Jun-Ichi; Nakagawa, Hiroshi; Akinaga, Shiro; Nakashima, Takayuki; Shiotsu, Yukimasa; Kajita, Jiro; Kanda, Yutaka; Nara, Shinji

Agent Spruson & Ferguson

Pub. Number AU-B-2004251949

PCT Pub. Number WO2005/000778

Priority 2003-185475 27.06.03 JP

Filing date 10 June 2004

Wipo publication date 6 January 2005

Acceptance publication date 7 May 2009

A61K 31/12 (2006.01) - Ketones

A61K 31/165 (2006.01) - having aromatic rings, e.g. colchicine, atenolol, progabide

A61K 31/216 (2006.01)

A61K 31/40 (2006.01) - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 31/4406 (2006.01) - only substituted in position 3, e.g. zimeldine

A61K 31/4409 (2006.01) - only substituted in position 4, e.g. isoniazid, iproniazid

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61K 31/451 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/5375 (2006.01) - 1,4-Oxazines, e.g. morpholine

A61K 31/5377 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07C 49/84 (2006.01) Ketones

C07C 69/738 (2006.01) Esters of carboxylic acids

C07C 205/45 (2006.01) Compounds containing nitro groups bound to a carbon skeleton

C07C 235/78 (2006.01) Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms

C07D 213/40 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 295/092 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/185 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms