Owner F. Hoffmann-La Roche AG

Inventors Chu, Chang An; Tilley, Jefferson Wright; Gillespie, Paul

Agent Spruson & Ferguson

Pub. Number AU-B-2004251846

PCT Pub. Number WO2005/000781

Priority 60/569,356 07.05.04 US; 60/480,900 24.06.03 US; 60/482,147 24.06.03 US

Filing date 18 June 2004

Wipo publication date 6 January 2005

Acceptance publication date 4 February 2010

A61P 5/48 (2006.01) Drugs for disorders of the endocrine system

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/40 (2006.01) - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 31/427 (2006.01) - not condensed and containing further heterocyclic rings

C07C 65/24 (2006.01) Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07D 213/79 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 277/56 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 307/68 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/40 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 405/06 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom