Owner AstraZeneca AB

Inventors Luker, Timothy; Thom, Stephen; Millichip, Ian; Pairaudeau, Garry; Brough, Stephen; Rasul, Rukhsana; McInally, Thomas; Patel, Anil; Bonnert, Roger; Davies, Andrew

Agent Freehills

Pub. Number AU-B-2004228599

PCT Pub. Number WO2004/089885

Priority 0301010-5 07.04.03 SE

Filing date 6 April 2004

Wipo publication date 21 October 2004

Acceptance publication date 5 June 2008

C07C 317/22 (2006.01) Sulfones

A61K 31/10 (2006.01)

A61K 31/192 (2006.01)

C07C 59/48 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 59/68 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 59/70 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 65/24 (2006.01) Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 69/94 (2006.01) Esters of carboxylic acids

C07C 205/35 (2006.01) Compounds containing nitro groups bound to a carbon skeleton

C07C 205/37 (2006.01) Compounds containing nitro groups bound to a carbon skeleton

C07C 217/80 (2006.01) Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

C07C 235/42 (2006.01) Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms

C07C 255/55 (2006.01) Carboxylic acid nitriles

C07C 271/28 (2006.01) Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07C 275/32 (2006.01) Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07C 311/29 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 317/28 (2006.01) Sulfones

C07C 323/18 (2006.01) Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

C07D 205/04 (2006.01) Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

C07D 207/02 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/61 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/71 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/72 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members