Metabotropic glutamate receptor antagonists for treating central nervous system diseases

Details for Australian Patent Application No. 2004202776 (hide)

Owner AstraZeneca AB

Inventors Moe, Scott T; Barmore, Robert; Shcherbakova, Irina; Sheehan, Susan M; Stormann, Thomas M; Van Wagenen, Bradford C; Trovato, Richard; Smith, Daryl L; Walton, Ruth; Delmar, Eric G

Agent Griffith Hack

Pub. Number AU-B-2004202776

Parent 771358

Filing date 17 June 2004

Wipo publication date 22 July 2004

Acceptance publication date 19 June 2008

International Classifications

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/4184 (2006.01)

A61K 31/425 (2006.01) - Thiazoles

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/428 (2006.01) - condensed with carbocyclic rings

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/4402 (2006.01) - only substituted in position 2, e.g. pheniramine, bisacodyl

A61K 31/4406 (2006.01) - only substituted in position 3, e.g. zimeldine

A61K 31/4409 (2006.01) - only substituted in position 4, e.g. isoniazid, iproniazid

A61K 31/4418 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61K 31/451 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine

A61K 31/454 (2006.01)

A61K 31/47 (2006.01) - Quinolines

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/498 (2006.01) - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine

A61K 31/505 (2006.01) - Pyrimidines

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07C 49/577 (2006.01) Ketones

C07C 225/04 Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a CHO group, e.g. amino ketones

Event Publications

8 July 2004 Complete Application Filed

22 July 2004 Application Open to Public Inspection

  Published as AU-B-2004202776

12 August 2004 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 23 Jul 2004

13 December 2007 Assignment before Grant

  NPS Pharmaceuticals, Inc. The application has been assigned to AstraZeneca AB

19 June 2008 Application Accepted

  Published as AU-B-2004202776

16 October 2008 Standard Patent Sealed

18 June 2009 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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