4-oxo-3-(1-oxo-1H-isoquinolin-2-ylacetylamino)-pentanoic acid ester and amide derivatives and their use as caspase inhibitors

Details for Australian Patent Application No. 2003303345 (hide)

Owner VERTEX PHARMACEUTICALS INCORPORATED

Inventors Charrier, Jean-Damien; Mortimore, Michael; Studley, John R.

Agent Cullens

Pub. Number AU-A-2003303345

PCT Number PCT/US2003/0408

PCT Pub. Number WO2004/058718

Priority 60/435,133 20.12.02 US

Filing date 22 December 2003

Wipo publication date 22 July 2004

International Classifications

C07D 217/24 Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

A61K 031/4725

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

C07D 405/12 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 417/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

A61K 031/472 - Non-condensed isoquinolines, e.g. papaverine

Event Publications

19 August 2004 Complete Application Filed

  Priority application(s): 60/435,133 20.12.02 US

26 August 2004 Application Open to Public Inspection

  Published as AU-A-2003303345

15 July 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(d). Examination has been requested or an examination report has issued for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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