Owner MILLENNIUM PHARMACEUTICALS, INC.

Inventors DAI, Mingshi; JENKINS, Tracy, J.; GUAN, Bing; GHOSH, Shomir; MINOR, Charles

Pub. Number AU-A-2003299883

PCT Number PCT/US2003/0411

PCT Pub. Number WO2004/058736

Priority 60/436,508 23.12.02 US

Filing date 23 December 2003

Wipo publication date 22 July 2004

C07D 295/26 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 031/4468 - having a nitrogen atom directly attached in position 4, e.g. clebopride, fentanyl

A61K 031/40 - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61P 011/06 Drugs for disorders of the respiratory system

A61P 029/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 037/08 Drugs for immunological or allergic disorders

C07D 213/42 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 211/58 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 207/14 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07C 311/46 Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

A61K 031/18 - Sulfonamides

A61K 031/4402 - only substituted in position 2, e.g. pheniramine, bisacodyl

A61K 031/4406 - only substituted in position 3, e.g. zimeldine

A61K 031/4409 - only substituted in position 4, e.g. isoniazid, iproniazid