Owner ONO PHARMACEUTICAL CO., LTD. MATSUZAWA, Yuji SHIMOMURA, Iichiro

Inventors MATSUZAWA, Yuji; IWAKI, Masanori; FUNAHASHI, Tohru; MAKISHIMA, Makoto; SHIMOMURA, Iichiro

Pub. Number AU-A-2003292822

PCT Number PCT/JP2003/0167

PCT Pub. Number WO2004/058970

Priority 2002-376589 26.12.02 JP

Filing date 25 December 2003

Wipo publication date 22 July 2004

C12N 015/11 Mutation or genetic engineering - DNA or RNA fragments

A61P 003/06 Drugs for disorders of the metabolism

A61P 009/12 Drugs for disorders of the cardiovascular system

G01N 033/15 Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

A61K 045/00 Medicinal preparations containing active ingredients not provided for in groups

C12Q 001/02 Measuring or testing processes involving enzymes or micro-organisms - involving viable micro-organisms

C12N 005/10 Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

G01N 033/566 Investigating or analysing materials by specific methods not covered by groups - using specific carrier or receptor proteins as ligand binding reagent

G01N 033/53 Investigating or analysing materials by specific methods not covered by groups - Immunoassay

G01N 033/50 Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine

A61P 031/10 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 009/10 Drugs for disorders of the cardiovascular system

A61P 003/04 Drugs for disorders of the metabolism