Owner Merck & Co., Inc.

Inventors Edmondson, Scott D.; Mastracchio, Anthony; Xu, Jinyou; Colandrea, Vincent J.; Mathvink, Robert J.; Weber, Ann E.

Agent Spruson & Ferguson

Pub. Number AU-B-2003290577

PCT Number PCT/US2003/0349

PCT Pub. Number WO2004/043940

Priority 60/501,232 19.06.03 US; 60/424,483 07.11.02 US

Filing date 3 November 2003

Wipo publication date 3 June 2004

Acceptance publication date 11 December 2008

C07D 205/04 (2006.01) Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

A61K 31/395 (2006.01) - having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins

A61K 31/40 (2006.01) - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

C07D 207/10 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 211/38 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 295/18 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/185 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 401/10 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups