Compositions comprising alternating 2'-modified nucleosides for use in gene modulation

Details for Australian Patent Application No. 2003287502 (hide)

Owner Isis Pharmaceuticals, Inc.

Inventors Baker, Brenda F.; Manoharan, Muthiah; Swayze, Eric E.; Allerson, Charles; Eldrup, Anne B.; Griffey, Richard H.; Bhat, Balkrishen

Agent Pizzeys

Pub. Number AU-B-2003287502

PCT Number PCT/US2003/0350

PCT Pub. Number WO2004/044136

Priority 60/423,760 05.11.02 US

Filing date 4 November 2003

Wipo publication date 3 June 2004

Acceptance publication date 9 December 2010

International Classifications

C07H 21/00 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

Event Publications

1 April 2004 Complete Application Filed

  Priority application(s): 60/423,760 05.11.02 US

8 July 2004 Application Open to Public Inspection

  Published as AU-B-2003287502

9 December 2010 Application Accepted

  Published as AU-B-2003287502

7 April 2011 Standard Patent Sealed

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