In Vivo gene silencing by chemically modified and stable siRNA

Details for Australian Patent Application No. 2003282877 (hide)

Owner University of Massachusetts

Inventors Rana, Tariq M.

Agent Watermark

Pub. Number AU-B-2003282877

PCT Number PCT/US2003/0304

PCT Pub. Number WO2004/029212

Priority 60/458,051 26.03.03 US; 60/426,982 15.11.02 US; 60/493,095 05.08.03 US; 60/413,529 25.09.02 US

Filing date 25 September 2003

Wipo publication date 19 April 2004

Acceptance publication date 7 April 2011

International Classifications

C07D 213/69 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

C12N 15/113 (2010.01) Mutation or genetic engineering - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

Event Publications

25 March 2004 Complete Application Filed

  Priority application(s): 60/458,051 26.03.03 US; 60/426,982 15.11.02 US; 60/493,095 05.08.03 US; 60/413,529 25.09.02 US

20 May 2004 Application Open to Public Inspection

  Published as AU-B-2003282877

7 April 2011 Application Accepted

  Published as AU-B-2003282877

4 August 2011 Standard Patent Sealed

19 April 2012 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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