Owner TAKEDA CHEMICAL INDUSTRIES, LTD.

Inventors KOYAMA, Nobuyuki; NOGUCHI, Kenichi; NISHIMURA, Atsushi; TAKIZAWA, Masayuki

Pub. Number AU-A-2003281314

PCT Number PCT/JP2003/0086

PCT Pub. Number WO2004/005512

Priority 2002-200509 09.07.02 JP; 2002-259177 04.09.02 JP

Filing date 8 July 2003

Wipo publication date 23 January 2004

C12N 015/09 Mutation or genetic engineering - Recombinant DNA-technology

C12N 001/15 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 001/19 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 001/21 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12P 021/02 Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

C12P 021/08 Preparation of peptides or proteins - Monoclonal antibodies

A61K 038/00 Medicinal preparations containing peptides

A61K 039/395 Medicinal preparations containing antigens or antibodies - Antibodies

A61K 048/00 Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 009/10 Drugs for disorders of the cardiovascular system

G01N 033/15 Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

G01N 033/50 Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine

C07K 014/47 Peptides having more than 20 amino acids

C07K 016/18 Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C12N 005/10 Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells