Owner FUJISAWA PHARMACEUTICAL CO., LTD.

Inventors UESHIMA, Koji; SAWADA, Masae; FURUKAWA, Yoshiro; MIKAMI, Masafumi; HINOUE, Kazumasa; FUKUMOTO, Daisuke; INOUE, Yoshikazu; TERASAWA, Takeshi; TAKASUGI, Hisashi; NAGAYOSHI, Akira

Pub. Number AU-A-2003274753

PCT Number PCT/JP03/13683

PCT Pub. Number WO2004/039795

Priority 2002952331 29.10.02 AU; 2003902622 27.05.03 AU

Filing date 27 October 2003

Wipo publication date 25 May 2004

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

C07D 295/14 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 409/14 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 277/48 Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

A61K 031/4406 - only substituted in position 3, e.g. zimeldine

A61K 031/4709 - Non-condensed quinolines containing further heterocyclic rings

A61K 031/472 - Non-condensed isoquinolines, e.g. papaverine

A61K 031/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61P 003/06 Drugs for disorders of the metabolism

C07D 401/14 Heterocyclic compounds containing two or more hetero rings

C07D 213/56 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/38 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/82 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/30 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/74 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/40 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/81 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 231/12 Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 249/08 Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 277/40 Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 213/75 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 417/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 403/12 Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 417/14 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 213/73 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 217/22 Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 207/32 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 403/04 Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 231/38 Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 209/08 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 409/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 405/12 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom