Owner GLAXO GROUP LIMITED

Inventors BEST, Desmond, John; BRUTON, Gordon; HEIGHTMAN, Thomas, Daniel; ORLEK, Barry, Sidney

Pub. Number AU-A-2003274053

PCT Number PCT/EP03/11649

PCT Pub. Number WO2004/037800

Priority 0224783.1 24.10.02 GB; 0303467.5 14.02.03 GB; 0224558.7 22.10.02 GB; 0224677.5 23.10.02 GB; 0224678.3 23.10.02 GB; 0224679.1 23.10.02 GB

Filing date 20 October 2003

Wipo publication date 13 May 2004

C07D 295/18 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 239/42 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/46 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 237/20 Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 215/46 Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 277/82 Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 241/08 Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 213/85 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 487/08 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 401/04 Heterocyclic compounds containing two or more hetero rings

C07D 307/14 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 241/20 Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 285/12 Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups

C07D 307/68 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/38 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 241/44 Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 285/14 Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups

C07D 261/18 Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

C07D 231/14 Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 307/24 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 309/08 Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings

C07D 307/85 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 211/52 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 207/14 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 498/10 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 471/10 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 221/20 Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

C07D 211/96 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 209/08 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/44 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

A61K 031/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61P 025/00 Drugs for disorders of the nervous system

C07D 295/22 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 243/08 Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms

C07D 213/74 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members