Owner METHYLGENE INC.

Inventors Vaisburg, Arkadii; Delorme, Daniel; Raeppel, Stephane; Paquin, Isabelle; Gaudette, Frederic

Agent Spruson & Ferguson

Pub. Number AU-A-2003273701

PCT Number PCT/CA03/01557

PCT Pub. Number WO2004/035525

Priority 60/419,688 17.10.02 US

Filing date 16 October 2003

Wipo publication date 4 May 2004

C07C 235/84 Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms

A61K 031/435 - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 031/495 - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61P 035/00 Antineoplastic agents

C07D 295/18 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07C 237/40 Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

C07D 295/14 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07C 233/80 Carboxylic acid amides

C07D 213/50 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/40 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/30 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 209/16 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 211/22 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 401/04 Heterocyclic compounds containing two or more hetero rings

C07D 213/74 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 277/82 Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 239/46 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 249/14 Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 317/66 Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms

C07D 213/38 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 209/44 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07C 311/19 Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

A61K 031/165 - having aromatic rings, e.g. colchicine, atenolol, progabide

A61K 031/40 - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil