Owner KOWA CO., LTD.

Inventors MATAKI, Chikage; KODAMA, Tatsuhiko; DOI, Takeshi; TAMURA, Masahiro; ODA, Toshiaki; OHKUCHI, Masao

Pub. Number AU-A-2003272973

PCT Number PCT/JP03/13047

PCT Pub. Number WO2004/032931

Priority 60/417,643 11.10.02 US

Filing date 10 October 2003

Wipo publication date 4 May 2004

A61K 031/495 - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

C07D 403/14 Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/14 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 409/14 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 263/32 Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D 243/08 Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms

A61K 031/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 031/506 - not condensed and containing further heterocyclic rings

A61K 031/551 - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61P 035/00 Antineoplastic agents

C07D 277/28 Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 277/40 Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 231/12 Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 401/14 Heterocyclic compounds containing two or more hetero rings

C07D 295/08 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 261/08 Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

C07D 233/61 Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 333/20 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 213/36 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 239/26 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 417/14 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group