Owner PHARMACIA CORPORATION

Inventors TOLLEFSON, Michael, B.; VANCAMP, Jennifer, Ann; COX, Phillip, B.; NIZAL, Chandrakumar, S.; DALTON, Christopher, R.; MALECHA, James, W.

Pub. Number AU-A-2003272552

PCT Number PCT/US03/29426

PCT Pub. Number WO2004/026816

Priority 60/436,240 23.12.02 US; 60/411,362 17.09.02 US

Filing date 17 September 2003

Wipo publication date 8 April 2004

C07C 323/56 Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

C07D 317/58 Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms

C07D 333/38 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

A61K 031/167 - having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol

A61P 009/04 Drugs for disorders of the cardiovascular system

C07C 323/60 Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

C07C 323/62 Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

C07D 213/70 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/81 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/82 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 295/14 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/18 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 307/14 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 307/52 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom