Owner SmithKline Beecham Biologicals S.A.

Inventors Voet, Pierre; Thonnard, Joelle; Thiry, Georges; Poolman, Jan; Lobet, Yves; Feron, Christiane; Dequesne, Guy; Denoel, Philippe; Dalemans, Wilfried L. J.; Berthet, Francois-Xavier Jacques

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2003270970

Parent 68336

Filing date 17 December 2003

Wipo publication date 22 January 2004

Acceptance publication date 26 May 2005

C12N 015/74 Mutation or genetic engineering - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

A61K 039/295 Medicinal preparations containing antigens or antibodies - Polyvalent viral antigens

A61K 039/102 Medicinal preparations containing antigens or antibodies - Pasteurella

A61K 039/104 Medicinal preparations containing antigens or antibodies - Pseudomonas

A61K 039/09 Medicinal preparations containing antigens or antibodies - Streptococcus

A61K 039/118 Medicinal preparations containing antigens or antibodies - Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci

A61K 039/116 Medicinal preparations containing antigens or antibodies - Polyvalent bacterial antigens

A61K 039/095 Medicinal preparations containing antigens or antibodies - Neisseria

C12N 015/67 Mutation or genetic engineering - General methods for enhancing the expression

C12N 015/31 Mutation or genetic engineering - Genes encoding microbial proteins, e.g. enterotoxins

A61K 039/02 Medicinal preparations containing antigens or antibodies - Bacterial antigens

C12N 001/21 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C07K 014/195 Peptides having more than 20 amino acids - from bacteria