Owner Genentech, Inc.

Inventors Davis, David P.; Wood, William I.; Zhang, Zemin; DeSauvage, Frederic J.

Agent Griffith Hack

Pub. Number AU-B-2003270348

PCT Number PCT/US03/27886

PCT Pub. Number WO2004/024063

Priority 60/410,166 11.09.02 US

Filing date 5 September 2003

Wipo publication date 30 April 2004

Acceptance publication date 26 August 2010

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 31/7105 (2006.01) - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61P 35/00 (2006.01) Antineoplastic agents

C07K 1/00 (2006.01) General processes for the preparation of peptides

C07K 14/47 (2006.01) Peptides having more than 20 amino acids

C07K 16/30 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 16/40 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against enzymes

C07K 19/00 (2006.01) Hybrid peptides

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 9/12 (2006.01) Enzymes, e.g. ligases (6.) - transferring phosphorus containing groups, e.g. kinases (2.7)

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies

C12Q 1/02 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving viable micro-organisms

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids