Owner Bristol-Myers Squibb Company

Inventors Ewing, William R.; Li, James J.; Sulsky, Richard B.; Li, Jun; Yu, Guixue; Tino, Joseph A.

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2003270065

PCT Number PCT/US03/27513

PCT Pub. Number WO2004/021984

Priority 60/491,645 31.07.03 US; 60/408,099 04.09.02 US

Filing date 2 September 2003

Wipo publication date 29 March 2004

Acceptance publication date 5 June 2008

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

A61K 31/415 (2006.01) - 1,2-Diazoles

A61K 31/42 (2006.01) - Oxazoles

A61K 31/425 (2006.01) - Thiazoles

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/50 (2006.01) - Pyridazines

A61K 31/505 (2006.01) - Pyrimidines

A61K 31/535 (2006.01) - having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines

A61K 31/54 (2006.01) - having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame

A61K 31/55 (2006.01) - having seven-membered rings, e.g. azelastine, pentylenetetrazole

C07D 231/56 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 261/20 (2006.01) Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 498/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 513/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

C07D 519/00 (2006.01) Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or