Owner TAKEDA CHEMICAL INDUSTRIES, LTD.

Inventors Kusaka, Masami; Shiraishi, Mitsuru; Miyawaki, Toshio; Yamamoto, Satoshi; Hara, Takahito; Kanzaki, Naoyuki

Agent Griffith Hack

Pub. Number AU-A-2003254993

PCT Number PCT/JP03/10228

PCT Pub. Number WO2004/016576

Priority 2002/235275 12.08.02 JP

Filing date 11 August 2003

Wipo publication date 3 March 2004

C07C 035/52 Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring

C07D 207/10 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 207/12 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 207/14 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 207/16 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 207/22 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 207/24 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/44 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 211/14 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/22 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/28 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/34 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/42 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/46 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/60 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/62 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/74 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 217/04 Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 231/04 Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 231/06 Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 261/04 Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

C07D 265/02 Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms

C07D 267/10 Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms

C07D 295/06 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/14 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 303/46 Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom

C07D 307/81 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/54 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 405/04 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/04 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 491/113 Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

A61K 031/045 - Hydroxy compounds, e.g. alcohols

A61K 031/277

A61K 031/336 - having three-membered rings, e.g. oxirane, fumagillin

A61K 031/402 - 1-aryl-substituted, e.g. piretanide

A61K 031/4025 - not condensed and containing further heterocyclic rings, e.g. cromakalim

A61K 031/4035

A61K 031/42 - Oxazoles

A61K 031/438 - the ring being spiro-condensed with carbocyclic or heterocyclic ring systems

A61K 031/4453 - only substituted in position 1, e.g. propipocaine, diperodon

A61K 031/451 - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine