Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use

Details for Australian Patent Application No. 2003247792 (hide)

Owner Nicox S.A.

Inventors EZAWA, Maiko; Lin, Chia-En; Stevenson, Cheri A.; Gaston, Ricky D.; Fang, Xinqin; Schroeder, Joseph D.; Wey, Shiow-Jyi; Richardson, Stewart K.; Letts, Gordon L.; Earl, Richard A.; Ranatunge, Ramani R.; Khanapure, Subhash P.; Garvey, David S.

Agent Peter Maxwell & Associates

Pub. Number AU-B-2003247792

PCT Number PCT/US03/21026

PCT Pub. Number WO2004/004648

Priority 60/418,353 16.10.02 US; 60/449,798 26.02.03 US; 60/393,111 03.07.02 US; 60/397,979 24.07.02 US; 60/456,182 21.03.03 US

Filing date 3 July 2003

Wipo publication date 23 January 2004

Acceptance publication date 24 September 2009

International Classifications

C07D 295/08 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/21 (2006.01) - Esters, e.g. nitroglycerine, selenocyanates

A61K 31/405 (2006.01)

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61P 1/00 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/04 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/10 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/14 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 3/04 (2006.01) Drugs for disorders of the metabolism

A61P 17/02 (2006.01) Drugs for dermatological disorders

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 27/02 (2006.01) Drugs for disorders of the senses

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 35/00 (2006.01) Antineoplastic agents

A61P 35/02 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07C 203/04 (2006.01) Esters of nitric or nitrous acid

C07C 205/40 (2006.01) Compounds containing nitro groups bound to a carbon skeleton

C07C 205/56 (2006.01) Compounds containing nitro groups bound to a carbon skeleton

C07C 219/10 (2006.01) Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton

C07C 229/42 (2006.01) Compounds containing amino and carboxyl groups bound to the same carbon skeleton

C07C 235/08 (2006.01) Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms

C07C 235/12 Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms

Event Publications

2 October 2003 Complete Application Filed

  Priority application(s): 60/418,353 16.10.02 US; 60/449,798 26.02.03 US; 60/393,111 03.07.02 US; 60/397,979 24.07.02 US; 60/456,182 21.03.03 US

11 March 2004 Application Open to Public Inspection

  Published as AU-B-2003247792

10 September 2009 Assignment before Grant

  Nitromed, Inc. The application has been assigned to Nicox S.A.

24 September 2009 Application Accepted

  Published as AU-B-2003247792

21 January 2010 Standard Patent Sealed

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