2-ureido-6-heteroaryl-3h-benzoimidazol e-4-carboxylic acid derivatives and related compounds as gyrase and/or topoisomerase IV inhibitors for the treatment of bacterial infections

Details for Australian Patent Application No. 2003245442 (hide)

Owner Vertex Pharmaceuticals Incorporated

Inventors Drumm, Joseph; Stamos, Dean; Liao, Yusheng; Deininger, David D.; Grillot, Anne-Laure; Oliver-Shaffer, Patricia; Charifson, Paul

Agent Cullen & Co

Pub. Number AU-B-2003245442

PCT Number PCT/US03/18401

PCT Pub. Number WO2003/105846

Priority 60/429,077 26.11.02 US; 60/388,665 13.06.02 US

Filing date 11 June 2003

Wipo publication date 31 December 2003

Acceptance publication date 5 February 2009

International Classifications

A61K 31/4439 (2006.01)

A61K 31/444 (2006.01)

A61K 31/50 (2006.01) - Pyridazines

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 45/06 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61P 1/04 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 11/00 (2006.01) Drugs for disorders of the respiratory system

A61P 13/02 (2006.01) Drugs for disorders of the urinary system

A61P 13/08 (2006.01) Drugs for disorders of the urinary system

A61P 17/00 (2006.01) Drugs for dermatological disorders

A61P 27/16 (2006.01) Drugs for disorders of the senses

A61P 31/04 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07C 275/06 (2006.01) Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

Event Publications

25 September 2003 Complete Application Filed

  Priority application(s): 60/429,077 26.11.02 US; 60/388,665 13.06.02 US

26 February 2004 Application Open to Public Inspection

  Published as AU-B-2003245442

5 February 2009 Application Accepted

  Published as AU-B-2003245442

4 June 2009 Standard Patent Sealed

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