Owner PHARMACIA CORPORATION

Inventors KALMAN, Monica, J.; VAN CAMP, Jennifer, Ann; MALECHA, James, W.; MIYASHIRO, Julie, M.; DECRESCENZO, Gary, A.; COLLINS, Joe, T.

Pub. Number AU-A-2003241601

PCT Number PCT/US03/16382

PCT Pub. Number WO2003/099769

Priority 10/444,349 23.05.03 US; 60/383,078 24.05.02 US

Filing date 23 May 2003

Wipo publication date 12 December 2003

C07C 259/06 Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups

A61P 009/10 Drugs for disorders of the cardiovascular system

A61P 025/28 Drugs for disorders of the nervous system

C07C 237/06 Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

C07C 229/48 Compounds containing amino and carboxyl groups bound to the same carbon skeleton

C07C 229/36 Compounds containing amino and carboxyl groups bound to the same carbon skeleton

C07C 229/18 Compounds containing amino and carboxyl groups bound to the same carbon skeleton

C07C 219/06 Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton

C07C 217/08 Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

C07C 215/16 Compounds containing amino and hydroxy groups bound to the same carbon skeleton

C07D 335/02 Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom

C07D 309/14 Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings

C07D 295/18 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/08 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 215/16 Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 213/38 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 211/58 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 207/16 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

A61K 031/221

A61K 031/165 - having aromatic rings, e.g. colchicine, atenolol, progabide

A61K 031/136 - having the amino group directly attached to the aromatic ring, e.g. benzeneamine

A61K 031/133 - having hydroxy groups, e.g. sphingosine

A61P 003/06 Drugs for disorders of the metabolism

A61P 003/10 Drugs for disorders of the metabolism