Owner KYOWA HAKKO KOGYO CO., LTD.

Inventors NAKASATO, Yoshisuke; OHTA, Kiminori; ARAI, Eri; SAKU, Osamu; KUSAKA, Hiroko; NAKANISHI, Satoshi; MANABE, Haruhiko; OGAWA, Akira

Pub. Number AU-A-2003235256

PCT Number PCT/JP03/04970

PCT Pub. Number WO2003/089410

Priority 2002-117841 19.04.02 JP

Filing date 18 April 2003

Wipo publication date 3 November 2003

C07D 207/327 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/81 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 215/36 Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 241/44 Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 295/155 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 307/68 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 213/82 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/89 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

C07D 295/185 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/192 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/26 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/215 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 271/113 Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms

C07D 285/08 Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups

C07D 487/04 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 257/02 Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

C07D 319/06 Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms

A61K 031/495 - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 031/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 031/497

A61K 031/506 - not condensed and containing further heterocyclic rings

A61K 031/551 - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61K 038/05 Medicinal preparations containing peptides - Dipeptides

A61K 031/498 - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine

A61K 031/535 - having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines

A61K 031/40 - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61P 001/04 Drugs for disorders of the alimentary tract or the digestive system

A61P 003/10 Drugs for disorders of the metabolism

A61P 009/10 Drugs for disorders of the cardiovascular system

A61P 011/06 Drugs for disorders of the respiratory system

A61P 013/12 Drugs for disorders of the urinary system

A61P 017/00 Drugs for dermatological disorders

A61P 017/06 Drugs for dermatological disorders

A61P 019/02 Drugs for skeletal disorders

A61P 025/00 Drugs for disorders of the nervous system

A61P 029/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 035/00 Antineoplastic agents

A61P 037/00 Drugs for immunological or allergic disorders

A61P 037/06 Drugs for immunological or allergic disorders

A61P 043/00 Drugs for specific purposes, not provided for in groups