Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds and the compounds as such

Details for Australian Patent Application No. 2003231765 (hide)

Owner Gilead Sciences, Inc.

Inventors Chen, Xiaowu; Kim, Choung U; Rowe, Tanisha D; Williams, Matthew A; Xu, Lianhong; Bryant, Clifford; Yu, Richard, H.; Lee, William A; Swaminathan, Sundaramoorthi; Becker, Mark M; Jin, Haolun; Arimilli, Murty N; Tario, James D; Chen, James M; Zhang, Lijun; Lin, Kuei-Ying; Nelson, Peter H; Zhang, Jiancun; Sparacino, Mark; Dastgah, Azar; He, Gong-Xin; Mitchell, Michael L; Fardis, Maria; Lee, Christopher P; Yang, Zheng-Yu; Mackman, Richard L; Pyun, Hyung-Jung; Wang, Jianying; Liu, Hongtao

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2003231765

PCT Number PCT/US03/12901

PCT Pub. Number WO2003/090690

Priority 60/375,779 26.04.02 US; 60/375,665 26.04.02 US; 60/375,622 26.04.02 US; 60/375,834 26.04.02 US

Filing date 25 April 2003

Wipo publication date 10 November 2003

Acceptance publication date 10 December 2009

International Classifications

C07D 213/75 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/4155 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/66 (2006.01) - Phosphorus compounds

A61K 31/665 (2006.01) - having oxygen as a ring hetero atom, e.g. fosfomycin

A61K 31/675 (2006.01) - having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

A61P 31/18 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 213/85 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 231/12 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 231/20 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 233/42 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 239/48 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/80 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 243/04 (2006.01) Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms

C07D 265/18 (2006.01) Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms

C07D 307/68 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 471/14 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 491/04 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

C07F 9/02 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

C07F 9/38 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

C07F 9/40 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

Event Publications

28 August 2003 Complete Application Filed

  Priority application(s): 60/375,779 26.04.02 US; 60/375,665 26.04.02 US; 60/375,622 26.04.02 US; 60/375,834 26.04.02 US

18 December 2003 Application Open to Public Inspection

  Published as AU-B-2003231765

10 December 2009 Application Accepted

  Published as AU-B-2003231765

8 April 2010 Standard Patent Sealed

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