Owner The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services

Inventors Murphy, Brian R.; Markoff, Lewis; Hanley, Kathryn; Whitehead, Stephen S.; Falgout, Barry; Blaney, Joseph

Agent Cullen & Co

Pub. Number AU-B-2003231185

PCT Number PCT/US03/13279

PCT Pub. Number WO2003/092592

Priority 60/377,860 03.05.02 US; 60/436,500 23.12.02 US

Filing date 25 April 2003

Wipo publication date 17 November 2003

Acceptance publication date 27 September 2007

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/00 (2006.01) Medicinal preparations containing antigens or antibodies

A61K 39/12 (2006.01) Medicinal preparations containing antigens or antibodies - Viral antigens

A61K 39/42 (2006.01) Medicinal preparations containing antigens or antibodies - viral

A61P 31/14 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

C07H 21/00 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/04 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 7/00 (2006.01) Viruses, e.g. bacteriophages

C12N 7/04 (2006.01) Viruses, e.g. bacteriophages - Inactivation or attenuation