Carbamic acid compounds comprising a piperazine linkage as HDAC inhibitors

Details for Australian Patent Application No. 2003229883 (hide)

Owner TopoTarget UK Limited

Inventors Gailite, Vija; Loza, Einars; Finn, Paul W.; Romero-Martin, Maria-Rosario; Starchenkov, Igor; Ritchie, James; Kalvinsh Ivars; Dikovska, Klara; Watkins, Clare J.; Lolya, Daina

Agent Griffith Hack

Pub. Number AU-B-2003229883

PCT Number PCT/GB03/01463

PCT Pub. Number WO2003/082288

Priority 60/369,337 03.04.02 US

Filing date 3 April 2003

Wipo publication date 13 October 2003

Acceptance publication date 11 June 2009

International Classifications

C07D 295/16 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 17/06 (2006.01) Drugs for dermatological disorders

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 209/14 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/16 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/18 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/42 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/36 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/74 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 241/04 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 295/18 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/185 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/192 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/22 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/26 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 317/58 (2006.01) Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms

C07D 333/60 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

Event Publications

14 August 2003 Complete Application Filed

  Priority application(s): 60/369,337 03.04.02 US

20 November 2003 Application Open to Public Inspection

  Published as AU-B-2003229883

11 June 2009 Application Accepted

  Published as AU-B-2003229883

8 October 2009 Standard Patent Sealed

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